Can Pep Guardiola's side bounce back from their Champions League disappointment?
The mercurial Londoners take on the relegation-threatened Merseysiders at Stamford Bridge.
The Gunners face another stern test of their title-contender credentials at the Emirates Stadium.
The Red Devils travel to the Vitality Stadium looking to increase their chances of a top-five finish.
Pep Guardiola's men can bounce back to the top of the table with a win at home to the Hatters.
The long-awaited dramatization of the post-apocalyptic Bethesda game classic will deliver all eight episodes.
Top-four chasing Spurs head to the City Ground.
The Blues look to build on their dramatic midweek win over Man United as they take on the rock-bottom Blades.
The old foes face each other once again at Old Trafford in a crucial game for both sides.
Villa look to bounce back from a midweek thrashing by Man City as they host the struggling Bees.